NHLBI
Catalog entries using this tag (links open the entry card on its page):
Entries
MVP — Cross-ancestry GWAS & meta-analysis
STAGE_PERIOD
2020–2023
DESCRIPTION
MVP expanded to >850k participants with diverse ancestry representation including substantial African American, Hispanic, and Asian cohorts. Large-scale cross-ancestry GWAS meta-analyses with FinnGen and UK Biobank across cardiovascular, metabolic, psychiatric, and aging-related traits. Demonstrated generalizability and ancestry-specific effects of genetic associations.
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TOPMed — Program launch & design
STAGE_PERIOD
2014–2016
DESCRIPTION
Trans-Omics for Precision Medicine (TOPMed) program launched by the NHLBI as part of the Precision Medicine Initiative. Designed to generate whole-genome sequencing data from diverse populations across NHLBI-funded cohort studies, integrating multi-omics data with detailed phenotypes to study heart, lung, blood, and sleep disorders.
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