Transcriptome

Comprehensive RNA-seq analysis of the human transcriptome across multiple cell lines, revealing pervasive transcription with 62% of the genome covered by processed transcripts, thousands of novel non-coding RNAs, and extensive RNA processing complexity.

FANTOM3 transcript annotation producing the mouse gene catalog based on physical cDNAs. Extended the cDNA collection and provided comprehensive transcript annotation, distinguishing protein-coding from non-coding RNAs and revealing the complexity of the mammalian transcriptome.

Comprehensive analysis of transcriptome variation across tissues and individuals, revealing that tissue identity is the primary driver of expression variation.

Long-read RNA sequencing across GTEx tissues revealed extensive transcriptome variation including novel isoforms, fusion transcripts, and full-length isoform structures.