Proteomics
Catalog entries using this tag (links open the entry card on its page):
- TOPMed — WGS freeze expansion & multi-omics integration — Projects
- UK Biobank — Olink proteomics flagship pQTL — Projects
- UK Biobank — Proteome PheWAS & MR — Projects
Entries
TOPMed — WGS freeze expansion & multi-omics integration
STAGE_PERIOD
2022–2025
DESCRIPTION
Continued expansion of TOPMed WGS to over 100k participants across >50 NHLBI cohort studies. Integration of whole-genome sequencing with epigenomics, transcriptomics, proteomics, and metabolomics data. Open access to sequencing data and variant annotations through the BRAVEO browser and dbGaP, serving as a critical resource for the global genetics community.
URL
UK Biobank — Olink proteomics flagship pQTL
PUBMED_LINK
STAGE_PERIOD
2023.10
DESCRIPTION
UK Biobank Pharma Proteomics Project (UKB-PPP) released Olink Proximity Extension Assay proteomics for ~53k participants, covering ~2,900 plasma proteins. Flagship pQTL resource for cis/trans protein QTL mapping.
URL
TITLE
Plasma proteomic associations with genetics and health in the UK Biobank
UK Biobank — Proteome PheWAS & MR
PUBMED_LINK
STAGE_PERIOD
2023.10
DESCRIPTION
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases, using pQTL data from UKB-PPP and other cohorts.
URL
TITLE
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases