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Nat Rev Cancer

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AI Agents in Cancer Research (AI Agents Cancer)

AI Agent Cancer Research Oncology Review Clinical AI Nat Rev Cancer
PUBMED_LINK
41526721
FULL NAME
Artificial Intelligence Agents in Cancer Research and Oncology - A Review
DESCRIPTION
A comprehensive review from Nature Reviews Cancer examining how AI agents (beyond traditional ML classifiers) are transforming cancer research and oncology. Covers LLM-powered agents for clinical decision support, drug discovery, treatment planning, and patient care, including agentic systems capable of logical reasoning, multi-step planning, and tool use in oncology contexts.
TITLE
Artificial intelligence agents in cancer research and oncology.
Main citation
Truhn D, Azizi S, Zou J, Cerda-Alberich L, Mahmood F, Kather JN. (2026) Artificial intelligence agents in cancer research and oncology. Nature Reviews Cancer, 26(4):256-269. doi:10.1038/s41568-025-00900-0. PMID 41526721
ABSTRACT
Since 2022, artificial intelligence (AI) methods have progressed far beyond their established capabilities of data classification and prediction. Large language models (LLMs) can perform logical reasoning, multi-step planning, and tool use, enabling a new paradigm of AI agents for cancer research and oncology. This review examines how AI agents are transforming clinical decision support, drug discovery, treatment planning, and patient care in oncology.
DOI
10.1038/s41568-025-00900-0