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Epigenomes

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Roadmap — Integrative analysis of 111 reference epigenomes

Epigenomes Reference ChromHMM
PUBMED_LINK
25693563
STAGE_PERIOD
2015
DESCRIPTION
Flagship Roadmap Epigenomics paper: integrative analysis of 111 reference human epigenomes from diverse cell types and tissues. Generated comprehensive maps of histone modifications, chromatin accessibility, DNA methylation, and RNA expression. Defined 15-chromatin-state models (ChromHMM) for each epigenome and developed the Epigenome Roadmap web portal. A foundational resource for understanding gene regulation in human health and disease.
URL
https://www.roadmapepigenomics.org/
TITLE
Integrative analysis of 111 reference human epigenomes