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Projects UK Biobank

Curation of UK Biobank — listings under the Projects tab.

Summary Table

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Baseline cohort & array genotyping

UK Biobank GWAS
STAGE_PERIOD
2006–2010+
DESCRIPTION
Recruitment of ~500,000 UK adults with questionnaire and physical measures; genome-wide array genotyping on the full cohort underpins most early GWAS and PRS applications.
URL
https://www.ukbiobank.ac.uk/

Linked health records & repeat phenotypes

UK Biobank Phenotypes
STAGE_PERIOD
ongoing
DESCRIPTION
Linkage to hospital episode statistics, death registers, primary-care and cancer data; repeated web/verbal questionnaires and in-person follow-ups deepen longitudinal phenotyping for PheWAS and risk modelling.
URL
https://www.ukbiobank.ac.uk/

Whole-exome sequencing

UK Biobank WES
STAGE_PERIOD
phased release
DESCRIPTION
Large-scale exome sequencing released in tranches; enables rare-coding variant association, gene-based tests, and integration with array/WGS layers on overlapping participants.
URL
https://www.ukbiobank.ac.uk/

Whole-genome sequencing

UK Biobank WGS
STAGE_PERIOD
phased release
DESCRIPTION
WGS on a large fraction of participants supports CNV analysis, short-variant refinement, and single-sample graph workflows; companion GWAS products (e.g. Pan-UKB) extend array-based analyses across ancestries.
URL
https://www.ukbiobank.ac.uk/

Omics & imaging layers

UK Biobank Multi-omics
STAGE_PERIOD
ongoing
DESCRIPTION
NMR metabolomics, Olink/SomaScan proteomics, and multimodal imaging (e.g. brain, cardiac, body composition) in large subsets; sample sizes differ by assay and enrich multi-trait and pathway analyses.
URL
https://www.ukbiobank.ac.uk/